Ergometrine
Dosages; See below
Combinations; See below
Ergometrine Brands
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Ergometrin | Macs Pharmaceuticals | Mac?s Pharmaceuticals Ltd | 0.5mg | 1 | Injection | per vial | KES 6.00 |
| Ergometrin | Macs Pharmaceuticals | Mac?s Pharmaceuticals Ltd | 0.5mg | 1000 | Tablet | per tablet | KES 1,450.00 |
| Ergometrin | Macs Pharmaceuticals | Mac?s Pharmaceuticals Ltd | 0.5mg | 1 | Injection | per vial | KES 6.00 |
| Ergometrine | Laborate | Harley's Limited | 0.5mg | 1 | Injection | per vial | KES 10.00 |
| U Met | Prism Life Sciences | Galaxy Pharmaceuticals Ltd | 0.5mg | 1 | Injection | per vial | KES 12.00 |
| Ergometrine More info | |
|---|---|
| Mode Of Action | Ergometrine is an ergot alkaloid with a short duration of action. It directly stimulates the uterine muscle to increase force and frequency of contractions. These contractions of the uterine wall around bleeding vessels at the placental site produce haemostasis. It also induces cervical contractions. Besides, it produces arterial vasoconstriction by stimulation of ?-adrenergic, serotonin receptors and inhibition of endothelial-derived relaxation factor release. |
| Drug Indication | Prophylaxis and treatment of postpartum and post-abortal haemorrhage; quickening of expulsion of uterine contents in case of incomplete abortion; diagnosis of angina pectoris by Cardiologist Specialists |
| Precautions | Breast-feeding |
| Contra-Indications | Pregnancy; hypersensitivity to the drug |
| Side Effects | Allergic reactions; coronary vasospasm; bradycardia; cardiac arrest; ventricular arrhythmias; myocardial infarction; dyspnea; severe hypertension; peripheral vasospasm; nausea; uterine cramping; vomiting; diarrhea; nasal congestion; headache; sweating; tinnitus; unpleasant taste. |
| Dosage | 1.M; inj 200-500mcg (onset of action 5-7 minutes. Duration of action is 45 minutes). 1.V inj 100-500mcg (onset of action is one minute) |
| Drug Category | DRUGS ACTING ON GENITO-URINARY SYSTEM |
| Drug Sub-Category | Drugs acting on uterus |